Fig. 4
From: Prokaryotic microvesicles Ortholog of eukaryotic extracellular vesicles in biomedical fields
Steps for the generation of OMVs and MVs in Gram-negative (A) and Gram-positive (B) bacteria, respectively. TEM image of production of MVs (black arrows) by Gram-negative bacterium Serratia marcescens (C). Samples were stained with 2% uranyl acetate solution and imaged at 60 kV (Scale bar: 100 nm). Reprinted adapted from [52]. (Copyright 1998, Journal of Bacteriology). Ultrastructural imaging revealed the formation of MVs (red arrows) on the cell wall of Staphylococcus aureus cultured in the Tryptic Soy Broth medium (Scale bar: 100 nm) [32]. (Copyright 2018, Nature Communications)