Tumor-derived small extracellular vesicles facilitate omental metastasis of ovarian cancer by triggering activation of mesenchymal stem cells

Table 1 The association between miR-320a expression and clinicopathological features in ovarian cancer patients

Variables	miR-320a expression in ovarian cancer				miR-320a expression in omentum
Variables	n	Low expression	High expression	P value	n	Low expression	High expression	P value
Age				0.691				0.661
≤ 49	24	14	10		23	17	6
> 49	39	26	13		31	20	11
Pathology				0.314				0.023
HGSOC	46	27	19		38	22	16
Non-HGSOC	17	13	4		16	15	1
FIGO stage				0.018				0.004
I – II	18	16	2		16	16	0
III – IV	45	24	21		38	21	17
Omentum metastasis				0.021				< 0.001
Absent	27	22	5		23	22	1
Present	36	18	18		31	15	16
Lymph node metastasis				0.033				0.084^*
Absent	49	35	14		41	31	10
Present	14	5	9		13	6	7
Appendix metastasis				0.081^*				0.056^*
Absent	52	36	16		44	33	11
Present	11	4	7		10	4	6

* fisher test
FIGO International Federation of Gynecology and Obstetrics, HGSOC high-grade serous ovarian cancer

ISSN: 1478-811X