Fig. 3

Female mice were randomly divided into four groups: CON (oil), BPA, DHEA, BPA + DHEA (n = 10 of each group). During the treatment for 21 days, body weight of mice was measured every day (A). B Body weight gain, C body fat, D body fat ratio, E body lean and F body lean ratio. G Blood glucose and H insulin levels for indicated treatment. I, J Oral glucose tolerance tests (OGTTs) (K, L) and insulin tolerance tests (ITTs) were performed on mice of the four groups. M The homeostasis model assessment of insulin resistance (HOMA-IR) index was calculated of four groups. Data are represented as the mean ± SEM. One-way ANOVA with a Tukey post hoc test. * P < 0.05; ** P < 0.01, and *** P < 0.001