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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation

Fig. 3

Paxillin knockout has no effect on the physiological structure and function of thoracic aorta. a, HE staining of transverse sections of the thoracic aorta in control and paxillin SMKO mice. Scale bar = 200 µm. b, 80 mM K+ depolarization-induced contraction in thoracic aorta shows no difference between control (n = 9) and paxillin SMKO mice (n = 9). c, Noradrenaline (NA)-induced contraction in thoracic aorta shows a dose-dependent manner from control (n = 3) and paxillin SMKO mice (n = 3).Cont: control mice; PXN KO: paxillin SMKO mice; ns: no significant

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Cell Communication and Signaling

ISSN: 1478-811X