Table 1 Immune factors and macrophages
From: Targeting the macrophage immunocheckpoint: a novel insight into solid tumor immunotherapy
Immune factors | Effects | Biological effects |
|---|---|---|
CD68 | Macrophage markers | Used for macrophage identification and recognition |
CD163 | Macrophage specific receptor, chemokine | Clearing free hemoglobin in the body, maintaining tissue homeostasis |
PD-L1 | Immune checkpoint molecule | Inhibiting T cell immune responses, regulating immune reactions |
CD47 | Antigen, which interacts with macrophage receptors | Inhibiting macrophage phagocytosis, assisting cells in evading phagocytosis |
CD24-Siglec-10 | CD24 and Siglec-10, surface molecules, and immunosuppressive receptors | Siglec-10 interacts with CD24 to inhibit macrophage activity and regulate immune responses |