Fig. 2
From: Crosstalk between protein post-translational modifications and phase separation
Crosstalk between PTMs and LLPS in the physiopathological process. The large brown semi-circular arrow denotes the illness circle’s ability to rotate, much like a turntable, which we call the “turntable model” here. Crosstalk between PTMs and LLPS has been implicated in numerous areas of illness and biological function, i.e., neurodegenerative diseases, tumors, viral infections, environmental stress, DNA damage repair, transcriptional regulation, signal transduction, and cell homeostasis of living organisms. Furthermore, each PTM is linked to a different disease or biological function, and vice versa