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Table 1 Characteristics of the study population

From: Neutrophil extracellular traps mediated by platelet microvesicles promote thrombosis and brain injury in acute ischemic stroke

Characteristics

Control

(n = 45)

AIS

(n = 45)

Age (years)

58.46 ± 10.4

57.48 ± 11.4

Male (n, %)

(75%)

(75%)

WBC (×109)

6.87 ± 1.32

10.05 ± 3.38*

 Neutrophils (%)

59.90 ± 6.57

75.2 ± 10.67*

 Monocytes (%)

3.42 ± 0.55

2.83 ± 0.92*

 Lymphocytes (%)

21.04 ± 7.25

20.8 ± 9.63*

 Eosinophils (%)

1.19 ± 0.67

1.2 ± 1.19

 Basophils (%)

0

0

Total cholesterol (mmol/l)

3.16 ± 0.52

4.37 ± 0.78

Triglycerides (mmol/l)

1.42 ± 0.41

1.52 ± 1.21

LDL (mmol/l)

1.58 ± 0.36

2.88 ± 0.76*

HDL (mmol/l)

0.82 ± 0.20

1.16 ± 0.29

NIHSS score

—

8.69 ± 5.67

Previous AIS or TIA (n)

—

5

Diabetes (n)

2

6

Hypertension (n)

—

11

Hypercholesterolemia (n)

0

12

Cigarette smoking (n)

0

14

Erythrocytes(×1012/l)

4.33 ± 0.35

4.74 ± 0.46

PLT (×109)

259.2 ± 62.29

221.52 ± 47.6*

PT (s)

11.24 ± 1.04

11.03 ± 0.78

APTT (s)

35.06 ± 2.70

31.99 ± 3.52

D-dimer (mg/l)

41.8 ± 25.4

263.07 ± 208.6*

Fibrinogen (mg/l)

2.46 ± 0.43

3.07 ± 0.52*

Pharmacological therapy

 Antiplatelet (n)

—

20

 Anticoagulant (n)

—

5

 Fibrinolysis (n)

—

25

 ACE inhibitor or ARB (n)

6

18

 Statin (n)

4

22

  1. The main clinical and laboratory features of 45 healthy controls and 45 patients diagnosed with stroke. Data are presented as numbers (percentages) or the median ± SD
  2. WBC White blood cells, PLTs Platelets
  3. *P < 0.05 vs. healthy control