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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Neutrophil extracellular traps mediated by platelet microvesicles promote thrombosis and brain injury in acute ischemic stroke

Fig. 1

NET markers in stroke patients before and after thrombolysis. NET markers nucleosome (a), MPO-DNA (b), NE-DNA (c) and H3Cit-DNA (d) were measured in plasma samples from healthy subjects (n = 45) and ischemic stroke patients (n = 45) by ELISA. e NET releasing cells, defined as CD15 + CD66b + MPO + H3Cit + groups and detected in whole blood samples from healthy subjects (n = 10) and AIS patients (n = 45). The flow cytometry gate is showed. f The rate of NET releasing cells in whole blood samples from each group. Neutrophils from healthy subjects (g) and AIS patients (h) were stained for MPO (green) and H3Cit (red) and observed by confocal microscopy. i The rate of NETosis in neutrophils from each group. The inset scale bars ine, f and h, Iiare 40 μm. Statistics, Mann-Whitney test (a-d, f, i). Data are presented as the mean ± SD. ****P < 0.0001

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Cell Communication and Signaling

ISSN: 1478-811X