Fig. 4
A Pie charts showing the distribution of H3K4me3 peaks across different genomic regions in human nasal epithelial cells and Th2 NP tissue. B Density of H3K4me3 peaks in the Th2 CRSwNP vs. HC and IL-4 vs. IL-4 + BCI-121 groups. C-E Top enriched GO terms for biological processes (BPs), molecular functions (MFs) and cellular components (CCs) associated with epithelial cells, HMT activity and transcription in the H3K4me3high group. F-G Top enriched GO terms related to the specific gene SMYD3 in primary human nasal epithelial cells (IL-4 vs. control groups), including BP and MF terms. H GO term enrichment analysis of biological processes, cellular components, and molecular functions to assess the biological function of the SMYD3 gene in NPs from Th2 CRSwNP patients