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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Inhibition of Dickkopf-1 enhances the anti-tumor efficacy of sorafenib via inhibition of the PI3K/Akt and Wnt/β-catenin pathways in hepatocellular carcinoma

Fig. 2

SOR + WAY treatment inhibited the invasion, migration and colony formation abilities of HCC cells. A Cell viability assay of diverse concentrations of SOR and SOR combined with WAY to Huh7 and Hep3B cells. B Hep3B WT and Hep3B DKK1 KO cells were treated with SOR for 24 h or 48 h. And then cell viability assay of diverse concentrations of SOR to Hep3B WT and Hep3B DKK1 KO cells was evaluated. C Invasion, D migration, and E long-term colony formation assay of Huh7 and Hep3B cells. Data are presented as the mean ± SD and performed in triplicate independently. Statistical significance is indicated by *P < 0.05, **P < 0.01, ***P < 0.001

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Cell Communication and Signaling

ISSN: 1478-811X