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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Inhibition of Dickkopf-1 enhances the anti-tumor efficacy of sorafenib via inhibition of the PI3K/Akt and Wnt/β-catenin pathways in hepatocellular carcinoma

Fig. 1

DKK1 is up-regulated in HCC. A DKK1 expression levels of non-tumor and tumor tissues were measured using TCGA datasets for HCC. B Serum DKK1 levels in healthy controls, patients with liver diseases, but without HCC and patients with HCC. C DKK1 expression levels were measured using IF staining in human liver tissues (magnification, 400 ×). D Transposon encoding indicated genes were delivered to the mouse liver using hydrodynamic tail vein injection. DKK1 expression levels were measured using IF staining in mouse liver tissues (magnification, 400 ×). Data are presented as the mean ± SD and performed in triplicate independently. Statistical significance is indicated by *P < 0.05, **P < 0.01, ***P < 0.001

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