Fig. 8
From: Autophagy-modulating biomaterials: multifunctional weapons to promote tissue regeneration
Autophagy-modulating biomaterials promote nerve regeneration. a Graphic illustration of the autophagy pathway and its impairment in CRND8 glial cells at two levels. b Western blotting for the quantification of LC3I and LC3II. c Immunoblots of pro-CatD and matu-CatD and their quantification (Reproduced with permission [90]; Copyright 2014, American Chemical Society). d Graphic illustration of NanoCA for TFEB-regulated cellular clearance of α-syn in experimental models of PD. e Schematic illustration of the effects of NanoCA on TFEB-mediated exosome release for α-syn clearance. f Western blotting of LC3II, TFEB, and LAMP1 in Neuro-2a cells after treatment with NanoCA (Reproduced with permission [150]; Copyright 2020, American Chemical Society). g XRD pattern of EuIII(OH)3 nanorods. h TEM image of EuIII(OH)3 nanorods. i Western blotting of soluble and insoluble GFP-Htt. j Western blotting of LC3I and LC3II in three types of cells treated with EuIII(OH)3 nanorods (Reproduced with permission [154]; Copyright 2014, Elsevier)