Fig. 5

Predictive proteins for invasion and proliferation capacity. a Predictive protein panel for invasion capacity (invasion panel). The columns marked with different colors and the gray barplots indicate the 54 EV samples with the invasion capacity measured for the cell line of origin (leukemia not included). The rows indicate the proteins, which were clustered hierarchically. Two defined clusters were separated from each other. b Predictive protein panel for proliferation capacity (proliferation panel). The columns marked with different colors and the gray barplots indicate the 60 EV samples with the doubling time (in hours) measured for the cell line of origin. The rows indicate the proteins, which were clustered hierarchically. Two defined clusters were separated from each other. It should be noted that higher doubling time means lower proliferation capacity as it indicates more time for cell division