Table 2 ITGB1 and its binding TF
From: Integrinβ-1 in disorders and cancers: molecular mechanisms and therapeutic targets
Cancer type | TF name | Interaction region | Function | Ref |
|---|---|---|---|---|
Pancreatic ductal adenocarcinoma (PDAC) | TF | |||
Gastric carcinoma (GC) | ZEB1 | (− 1166 to − 1074) and (+ 9913 to + 10,010) | Promotes transcription | [51] |
Hepatocellular carcinoma (HCC) | FOXO3a | Inhibits transcription | [39] | |
TFEB | Inhibits transcription | [52] | ||
Colorectal carcinoma (CRC) | YY1 | Promotes transcription | [53] | |
Breast cancer (BC) | SRF | Promotes transcription | [54] | |
FOXM1 | Promotes transcription | [55] | ||
HIF-1α | Promotes transcription | [56] | ||
EZH2 | Promotes transcription | [57] | ||
Lung cancer (LC) | RBP2 | Promotes transcription | [58] | |
Oral squamous cell carcinoma (OSCC) | ZNF750 | Inhibits transcription | [59] | |
Ovarian cancer (OC) | ZNF304 | -3392 to -3297 | Promotes transcription | [60] |