Skip to main content

Table 1 ITGB1 and its binding proteins

From: Integrinβ-1 in disorders and cancers: molecular mechanisms and therapeutic targets

Interaction protein

Interaction region

Function

Ref

DCBLD2

 

Promotes EMT and angiogenesis

[44]

Caveolin-1

 

Promotes EMT and invasion

[45]

c-Met

Extracellular domains

Increases ligand-independent phosphorylation of c-Met

[46]

Osteopontin (OPN)

 

CAF recruitment

[47]

Periostin (POSTN)

 

Promotes the PI3K/AKT and Src pathways

[48, 49]

TIMP1

 

Activation of the PI3-K signaling pathway

[50]

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X