Fig. 3
From: Function and regulation of RGS family members in solid tumours: a comprehensive review
Basic structure and different structural domains of RGS proteins. A Basic structural domains of the RGS A/RZ subfamily, which contains RGS 17, RGS 19 and RGS 20. Red: RGS-Box (RGS domain). B Basic structural domains of the RGS B/R4 subfamily, which contains RGS 1–5, RGS 8, RGS13, RGS16, RGS18 and RGS 21. Red: RGS-Box (RGS domain). For RGS3, yellow: C2 domain, red: RGS-Box, purple: PDZ domain. C Basic structural domains of the RGS C/R7 subfamily, which contains RGS6, RGS7, RGS9 and RGS11. Green: DEP domain, grey: G protein domain, red: RGS-Box. D Basic structural domains of the RGS D/R12 subfamily, which contains RGS10, RGS12 and RGS14. Purple: PDZ domain, blue: PID domain, red: RGS-Box, green: RBD1 domain, yellow: RBD2 domain, orange: Goloco domain