Fig. 5

Depletion of Prx II inhibits STAT signaling pathway by regulating Foxo1-induced expression of miR-221. A Quantification of miR-221 expression in Prx II ^+/+ and Prx II ^−/− DMSCs using qRT-PCR analysis. B Venn diagrams of the target miRNAs of STAT1 and STAT2 predicted by TarBase. C qRT-PCR was used to measure the expression of the various miRNAs of TarBase in Prx II ^+/+ and Prx II ^−/− DMSCs. D Venn diagrams of the target miRNAs of STAT1 and STAT2 predicted by StarBase. E qRT-PCR was used to measure the expression of the various miRNAs of starBase. F Venn diagrams of the target miRNAs of STAT1 and STAT2 predicted by miRDB. G qRT-PCR was used to measure the expression of the various miRNAs of miRDB. *P < 0.05, **P < 0.01, as determined by two-tailed t test