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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: Comparative immunological landscape between pre- and early-stage LUAD manifested as ground-glass nodules revealed by scRNA and scTCR integrated analysis

Fig. 8

Functional analysis of Mono-like MAC subclusters. A. DEGs between Mono-like MAC isolated from nLung and AIS/IAC (Top). Significantly enriched Hallmark pathways in Mono-like MAC isolated from nLung or AIS/IAC as determined by GSVA score (Bottom). B. Significantly enriched metabolism-related pathways in Mono-like MAC isolated from nLung or AIS/IAC as determined by GSVA score. C. Representative immunofluorescence images showing FABP3 and FABP4 expression on macrophages in normal tissues and LUAD manifested as GGN. CD68 were stained red, FABP3 and FABP4 were stained green, and nuclei were stained blue (DAPI). Abbreviation: AIS: Adenocarcinoma in situ; DEG: Differential expressed gene; GSVA: Gene set variation analysis; IAC: Invasive adenocarcinoma

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Cell Communication and Signaling

ISSN: 1478-811X