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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Comparative immunological landscape between pre- and early-stage LUAD manifested as ground-glass nodules revealed by scRNA and scTCR integrated analysis

Fig. 6

Functional characteristics of different T/NK subclusters. A Ridge plot showing the naïve score, effector, and exhaustion score across different T/NK subclusters, arranged in descending order from top to bottom based on the logged expression values of each score. B The differential expression of different functional scores across different groups. Red boxes highlight the decrease of cytotoxic score along the progression of disease. C Genes significantly correlated with cytotoxic score in all groups of CD8 + T cells and differentially expressed in CD8 + T cells from AIS/IAC compared with nLung. Green bars indicated genes that are positively correlated with cytotoxic score and downregulated in CD8 + T cells from AIS/IAC; Blue bars indicated genes that are negatively correlated with cytotoxic score and upregulated in CD8 + T cells from AIS/IAC; length of the bar indicated the value of Pearson correlation coefficient

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Cell Communication and Signaling

ISSN: 1478-811X