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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Comparative immunological landscape between pre- and early-stage LUAD manifested as ground-glass nodules revealed by scRNA and scTCR integrated analysis

Fig. 1

Overview of cells in major clusters. A Flow chart of the study design. B TSNE plot of 38,814 cells, colored according to cell types (Top left), according to origin of the cells (Topright),andsplitbytheoriginofthecellsrespectively (Bottom). Each dot represents a single cell. C TSNE plot of 38,814 cells colored by number of UMIs RNA and genes detected. Each dot represents a cell. D Canonical markers expression across major cellclusters. E The proportion of cellular composition in different patients’ groups. F Percentage of each cell type in different groups. Error bars represent mean ± SEM. Colored dots represent different samples. Differences with p < 0.05 were indicated; two-sided unpaired Wilcoxon rank sum test was used for comparison. Abbreviation: TSNE: T-distributed Stochastic Neighbor Embedding; SEM: Standarderrorofmean; UMI: UniqueMolecularIdentifier; * p < 0.05

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