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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: L-Fucose promotes enteric nervous system regeneration in type 1 diabetic mice by inhibiting SMAD2 signaling pathway in enteric neural precursor cells

Fig. 6

 L-Fucose promoted ENPCs differentiation through inhibiting SMAD2 signaling pathway. A Immunofluorescence confocal laser images of GFP-labeled ENPCs (green) and p-SMAD2 (red) in each group in transverse sections of colon tissue; the nuclei (blue). Arrows represent double-labeled p-SMAD2+ GFP+ ENPCs. B Immunofluorescence staining of p-SMAD2 in ENPCs treated with glucose and L-Fucose. Arrows represent p-SMAD2+ expression. Con: the control mice or primary ENPCs cultures; DM: diabetic mice; DM + Fuc: diabetic mice administrated with L-Fucose; Glu: ENPCs treated with 30 mM glucose; Fuc: ENPCs treated with 30 mM glucose and 30 mg/ml L-Fucose. ENPCs, enteric neural precursor cells

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Cell Communication and Signaling

ISSN: 1478-811X