Fig. 9
From: Allergen-induced CD11c + dendritic cell pyroptosis aggravates allergic rhinitis
Adoptive transfer of OVA-loaded BMDCs significantly promoted allergic inflammation, while the administration of NSA to OVA-loaded BMDCs significantly reduced AR inflammation. A Experimental protocol for the construction of an adoptive transfer animal model. B Symptomatic scores in each group. C Serum levels of OVA-sIgE in each group. D Histopathological changes in the nasal mucosa; the arrow indicates eosinophils (400X). E Proliferation of goblet cells in the nasal mucosa; the arrow indicates proliferating goblet cells (200X). F Eosinophils or proliferating goblet cells were counted at a high magnification. G Levels of the cytokines IL-4, IL-5, and IL-13 in each group. *P < 0.05 and **P < 0.01 ***P < 0.001 ****P < 0.0001