Fig. 8
From: Allergen-induced CD11c + dendritic cell pyroptosis aggravates allergic rhinitis
Effects of BMDC pyroptosis on Th1/Th2/Th17 cell differentiation during the allergic inflammatory response. A-C The numbers of Th1 cells (CD4 + T-bet+), Th2 cells (CD4 + GATA3+) and Th17 cells (CD4 + RORγt+) in the lymphocyte populations in each group. D ~ F Gene expression of T-bet, GATA3, and RORγt in the cocultures was determined by quantitative real-time PCR. G ~ H Levels of the cytokines IL-2, IFN-γ, IL-6 and IL-17 A in the supernatant of cells cocultured with lymphocytes in each group. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001