Fig. 5
From: Allergen-induced CD11c + dendritic cell pyroptosis aggravates allergic rhinitis
Inhibiting pyroptosis alleviated the inflammatory response in the AR model. A Experimental procedure. B Allergic symptom scores in each group. C OVA-specific serum IgE titres in each group. D Quantification of eosinophil infiltration. E Quantification of goblet cell hyperplasia. F Nasal mucosal sections were stained with haematoxylin and eosin (H&E), and the arrows indicate eosinophils (400X). G Nasal mucosal sections were stained with periodic acid–Schiff reagent (PAS), and the arrows indicate goblet cells (400X). H Statistical analysis of the concentrations of IL-2, IFN-γ, IL-4, IL-6 and IL-17 A in each group. The values represent the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. The data from three independent experiments are presented. AR, allergic rhinitis; NSA, necrosulfonamide