Fig. 3
From: Allergen-induced CD11c + dendritic cell pyroptosis aggravates allergic rhinitis
Pyroptosis was significantly increased in CD11c + DCs in the nasal mucosa of AR mice, and NSA treatment attenuated CD11c + DC pyroptosis. A Immunofluorescence analysis of CD11c-positive cells, GSDMD-N-positive cells and CD11c and GSDMD-N double-positive cells in the nasal mucosa of mice in the control group. B Immunofluorescence analysis of CD11c-positive cells, GSDMD-N-positive cells and CD11c and GSDMD-N double-positive cells in the nasal mucosa of mice in the AR group. C Immunofluorescence analysis of CD11c-positive cells, GSDMD-N-positive cells and CD11c and GSDMD-N double-positive cells in the nasal mucosa of mice in the AR + NSA group. The arrows indicate CD11c and GSDMD-N double-positive cells. D The serum expression levels of IL-1β and IL-18 in each group. *P < 0.05 ***P < 0.001 ****P < 0.0001