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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles

Fig. 6

Comparison of plasma EVs from MS patients in a relapse versus in a stable disease phase. Relative EV Neuro signal intensities as signal of target divided by the total signal of all markers (in %) for immuno-affinity captured CD63+EVs (a) and CD81+EVs (b). Bars represent mean values and error bars indicate the 95% confidence interval. Asterisks mark statistically significant differences between stable phase and disease relapse. Only significant alterations of targets that were consistently detected above background in all individuals are marked. *=p < .05, **=p < .01

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