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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Insight into extracellular vesicles in vascular diseases: intercellular communication role and clinical application potential

Fig. 5

Intercellular communication that EV cargoes mediate regulates the tumor progression

As tumors such as hemangiomas, hematological malignancies, and other solid tumors advance, cargoes from various donor cells, including mesenchymal stem cells (MSCs), cancer cells, macrophages, and fibroblasts can activate or inhibit specific targets in recipient cells. These processes affect tumor development by regulating cell proliferation, apoptosis, angiogenesis, metastasis, and drug resistance

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