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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Insight into extracellular vesicles in vascular diseases: intercellular communication role and clinical application potential

Fig. 4

Intercellular communication that EV cargoes mediate regulates diabetic complication progression

Cargoes from different donor cells, including tubular epithelial cells (TECs), macrophages, mesenchymal stem cells (MSCs), adipose-derived stem cells (ADSCs), platelets, retinal Muller cells, pericytes, adipocytes, cardiomyocytes, cardiac microvascular endothelial cells (CMECs), and epidermal cells can activate or inhibit the specific targets in recipient cells during the progression of diabetic complications, including diabetic nephropathy (DN), diabetic retinopathy (DR), diabetic cardiomyopathy (DCM), and diabetic foot ulcers (DFU). These processes affect cell apoptosis, autophagy, angiogenesis, and inflammation

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Cell Communication and Signaling

ISSN: 1478-811X