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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Insight into extracellular vesicles in vascular diseases: intercellular communication role and clinical application potential

Fig. 3

Intercellular communication that EV cargoes mediate regulates cardiovascular disease progression

Cargoes from different donor cells, including endothelial cells (ECs), adventitial fibroblasts, monocytes, macrophages, cardiomyocytes, and stem cells can activate or inhibit specific targets in recipient cells during cardiovascular disease progression, including hypertension, atherosclerosis, acute myocardial infarction (AMI), myocardial ischemia–reperfusion injury (MIRI), and heart failure (HF). These processes affect cell proliferation, apoptosis, vascular remodeling, angiogenesis, inflammation, and fibrosis in cardiovascular diseases

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Cell Communication and Signaling

ISSN: 1478-811X