Fig. 2From: Unveiling the mechanisms and challenges of cancer drug resistanceRole of CSC in drug resistance and relapse by altering its microenvironment and modifying the host immune system. CSCs are resistant to various therapies compared to cancer cells by activating various survival pathways and also changing their microenvironment like increasing autophagy as well as secreting various chemokines and cytokines which in turn cause drug resistance. Figure created with BioRender.comBack to article page