Table 1 Novel anticancer genes identified through functional genetic screen
From: Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC
ACG index | Clone ID | GenBank accession number | Gene symbol | Gene ID | Protein coding? |
|---|---|---|---|---|---|
1 | 1B01 | AK074989 | ZNF436-AS1 | ZNF436 antisense RNA | No |
2 | 4G04 | AK026893 | nda | Novel-ACG4G4 (A novel transcript overlapping to intronic region of HHLA2) | nd |
3 | 3C09 | AK091900 | SMLR1 | Small leucine-rich protein 1 | Yes |
4 | 4G03 | AK024890 | nd | Novel-ACG4G3 (A novel transcript overlapping to PYHIN1) | nd |
5 | 3B03 | AK127225 | nd | Novel-ACG3B3 | nd |
6 | 1A03 | AK074632.1 | TMEFF2 | Transmembrane protein with EGF-like and two follistatin-like domains 2 | Yes |
7 | 2B08 | AK055260 | LINC01529 | Long intergenic non-protein coding RNA 1529 | No |
8 | 3B06 | AK127945 | HYAL2 | Hyaluronoglucosaminidase 2 | Yes |
9 | 2A05 | AK056206 | NEIL2 | Nei-like DNA glycosylase 2 | Yes |
10 | 1B08 | AK075147 | FBLN5 | Fibulin 5 | Yes |
11 | 2H03 | AK124577 | YPEL4 | Yippee-like 4 | Yes |
12 | 4E06 | AK024927.1 | nd | Novel-ACG4E6 (ENSG00000261116 lncRNA- overlapping to FAM83B) | No |
13 | 3D05 | AK092480 | PHKA2 | Non-coding, processed transcript | No |
14 | 4F06 | AK024692 | LRRFIP2 | Leucine rich repeat (in FLII) interacting protein 2. Partial overlap—last seven exons | nd |
15 | 4F04 | AK024913 | nd | Novel-ACG4F4 (A novel transcript overlapping to CCDC6) | nd |
16 | 4D09 | AK024690 | nd | Novel-ACG4D9 (A novel transcript overlapping to FBXL20) | nd |