Fig. 8From: Identification of novel SCD1 inhibitor alleviates nonalcoholic fatty liver disease: critical role of liver-adipose axisA proposed mechanism by which E6446 prevents nonalcoholic fatty liver disease (NAFLD). E6446 target the liver-adipose axis to suppress SCD1-ATF3 signaling, which mediates adipogenic differentiation and hepatic lipogenesisBack to article page