Fig. 4
From: Castration promotes the browning of the prostate tumor microenvironment
Effect of RSGZ treatment for 6 weeks in the prostate tumor microenvironment. A iBAT weight vs body weight ratio in WT and TRAMP mice after RSGZ administration. B Body temperature in WT and TRAMP after 6 weeks of RSGZ treatment. C Morphometric analysis of PPAT: adipocyte average area (left panel), WAT surface vs gland (central panel), brown/beige fat surface vs gland (right panel) (D) Effect of RSGZ treatment on the GU vs body weight ratio (right panel) (E) Effect of RSGZ treatment for 6 weeks in the prostate epithelial cells proliferation by EdU Images were taken at 400X of magnification. F Number of positive cells for EdU vs DAPI surface 5 different images form each mouse were used for the quantification. n = 5. Data were represented as mean ± SEM. * p < 0.05, ** p < 0.01, **** p < 0.0001