Fig. 7
From: Therapeutic targeting of the TPX2/TTK network in colorectal cancer
Differential expression and gene set enrichment analysis in TTKhigh COAD. a Heat map clustering of 512 COAD transcripts stratified according to median TTK expression. b GO enrichment tree in the same cohort of COAD according to median TTK expression. Enrichment p value is indicated for each functional category. c Bubble chart illustrating activated (orange) and suppressed (blue) canonical pathways in TTKhigh vs TTKlow COAD employing IPA analysis. Size of the bubble corresponds to the number of genes that overlap the pathway. X-axis represents the -log p-value