Fig. 6
From: Therapeutic targeting of the TPX2/TTK network in colorectal cancer
Differential expression and gene set enrichment analysis in TPX2high COAD. a Heat map clustering of 512 COAD transcripts stratified into high vs low according to median TPX2 expression. b GO enrichment tree in the TPX2high vs TPX2low COAD. Enrichment p value is indicated for each functional category. c Bubble chart illustrating activated (orange) and suppressed (blue) canonical pathways in TPX2high vs TPX2low COAD employing IPA analysis. Size of the bubble corresponds to the number of genes that overlap the pathway. X-axis represents the -log p-value