Fig. 3
From: Therapeutic targeting of the TPX2/TTK network in colorectal cancer
Dead-live staining of HT-29 and HCT116 CRC models in response to TPX2, TTK, DDX39A and LRP8 depletion. Representative fluorescence images for CRC cells post-siRNA-mediated knockdown of TPX2, TTK, DDX39A or LRP8. Cells were stained on day 4 with AO/EtBr to detect live (green) cells (first panel) and dead cells (red; necrotic) shown in the second panel. Third panel shows the merged images