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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Preeclampsia impedes foetal kidney development by delivering placenta-derived exosomes to glomerular endothelial cells

Fig. 4

Function of trophoblast-derived exosomes on foetal mouse kidney. A Schematic diagram of culture process. B In vivo imaging system showed that DIR-labelled exosomes were internalized by Fetal mouse. C Appearance of fetal mice. D Foetal mice weight. E Glomerular numbers of foetal mice. F Staining of kidney segmens with PAS, Scale: 50 μm. G IHC of the expression of VE-cadherin, Scale: 20 μm. H IHC of the expression of Occludin, Scale: 20 μm. I Western blot of VE-cadherin and Occludin. J, qRT-PCR of the expression of VE-cadherin and Occludin. Values are presented as means ± SD, **P < 0.01, ***P < 0.001 ****P < 0.0001

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Cell Communication and Signaling

ISSN: 1478-811X