Fig. 6
From: Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML
O-GlcNAcylation on TWIST1 affect the DAC resistance of MDS clone cells. A The scheme of the xenotransplantation mouse model. B FACS analysis of percentages of hCD45+ cells in peripheral blood. C Overall survival curve of mice injected KG1a-KO-TWIST1-WT or KG1a-KO-TWIST1-mutation. D The xenotransplantation mouse model. E FACS analysis for percentages of KG1a-TWIST1 cells in peripheral blood. F Overall survival curve of mice injected with KG1a cells and treated with DAC ± OSMI-1. **p < 0.01, ns: not significant