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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: The mechanism of oleic acid inhibiting platelet activation stimulated by collagen

Fig. 6

Oleic acid inhibits intracellular platelet signal transduction. A-B Washed human platelets are pretreated with oleic acid (0 µM, 4 µM, 10 µM), stimulated with collagen, and subsequently lysed with lysis buffer. Western blotting is performed to assess the phosphorylation levels of PLCγ2, Syk, PI3K (Y607), Akt (Ser473), ERK1/2, and p38; N = 5. Data are presented as mean ± standard error of mean; one-way analysis of variance; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, NS indicates no statistical significance

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