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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: RU.521 mitigates subarachnoid hemorrhage-induced brain injury via regulating microglial polarization and neuroinflammation mediated by the cGAS/STING/NF-κB pathway

Fig. 7

RU.521 promoted microglial M1-to-M2 phenotypic polarization in vitro. A-C Western blot bands and quantitative analysis for target protein expression in BV2 cells. n = 3 per group. D-G Representative images of immunofluorescence staining and quantitative analysis for CD16, CD206, and TNF-α. Scale bar = 50/100 μm. n = 3 per group. *: P < 0.05, **: P < 0.01, ***: P < 0.001, and ****: P < 0.0001. ns, not significant

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