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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: RU.521 mitigates subarachnoid hemorrhage-induced brain injury via regulating microglial polarization and neuroinflammation mediated by the cGAS/STING/NF-κB pathway

Fig. 6

RU.521 inhibited neuronal damage in vitro. A Illustration of the co-culture system. B, D Representative western blot bands and quantitative analysis of the expression of cleaved-caspase 3 for TH22 cells. n = 3 per group. C, E Representative flow cytometry plots for HT22 cells. The apoptosis rate is calculated by the proportion of PI +/Annexin V+ plus PI −/Annexin V+. n = 3 per group. F Quantitative analysis of cell viability detected by CCK8 assays. n = 3 per group. *: P < 0.05, **: P < 0.01, ***: P < 0.001, and ****: P < 0.0001. ns, not significant

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Cell Communication and Signaling

ISSN: 1478-811X