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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: RU.521 mitigates subarachnoid hemorrhage-induced brain injury via regulating microglial polarization and neuroinflammation mediated by the cGAS/STING/NF-κB pathway

Fig. 5

RU.521 promoted the recovery of neurological function and dendritic spine densities. A, B Analysis of the modified Garcia scores and beam balance scores of each group. n = 6 per group. C, D Escape latency and swim distance in the visible platform trial of the water maze test. n = 6 per group. E Escape latency in the hidden platform trial of the water maze test. n = 6 per group. F–H The times each animal crossed the original position of the platform, swimming speed, and swimming path in the probe trial of the water maze test. n = 6 per group. I, J Representative images of Golgi staining for dendritic spine densities and the analysis results. Scale bar = 2 μm. n = 6 per group. *: P < 0.05, **: P < 0.01, ***: P < 0.001, and ****: P < 0.0001. &: P < 0.05, &&: P < 0.01, &&&: P < 0.001, and &&&&: P < 0.0001. #: P < 0.05, ##: P < 0.01, ###: P < 0.001, and ####: P < 0.0001. ns, not significant

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Cell Communication and Signaling

ISSN: 1478-811X