Fig. 2

ALS- and LPS-induced Golgi apparatus stress response. (A) Schematic presentation of the Golgi-mediated stress response pathway in the testis after administration of ALS and LPS with ALS expression of proteins involved inCREB34, HSF47 and TFE3-mediated pathways evaluated with Western blot method (B), i.e.: CREB34L (C), ARF4 (D), HSP47 (E), TFE3 (F), SIAT4A (G), GRASP65 (H), WIPI1 (I), GCP60 (J), giantin (K). Bars indicate mean \(\pm\) SD, n = 6 per each group; (*) indicate comparison between control and analyzed groups after MTEP, NS-398, IMI, MTEP + NS-398, IMI + NS-398 with and without LPS; (^) indicate comparison after administration the same substances between the groups without and with LPS; ***/^^^ p < 0.001, **/^^ p < 0.01, */^ p < 0.05; no indication = no statistical significance (one-way ANOVA with Dunnett’s post hoc test). The results were normalized to β-actin