Fig. 4From: Functional diversity of c-di-GMP receptors in prokaryotic and eukaryotic systemsDownstream signaling induced by bacterial c-di-GMP binding to STING cognate receptors leads to the generation of type I IFNs through the IFN regulatory factor 3 and TANK-binding kinase 1 pathway. Reprinted with permission from the reference [129]. Copyright, 2012 Elsevier IncBack to article page