Fig. 4

Inhibition of NETs alleviates neuroinflammation of CFA mice. A and C. Representative images and quantification of GFAP⁺ astrocytes in spinal cord sections (n = 3, scale bars: 50 or 100 μm). B and D. Representative images and quantification of IBA1⁺ microglia in spinal cord sections (n = 3, scale bars: 50 or 100 μm). E–G. ELISAs detecting IL-1β, IL-6, and TNF-α in the spinal cords of mice (n = 5). The expression in the vehicle group was set to 1 for quantification. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, compared with the vehicle group mice