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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma

Fig. 3

Transcriptomic analysis revealed that RNF173 participated in EMT. A RNA sequencing analysis of three samples each from the negative control and RNF173 knockdown groups resulted in a heatmap of 1055 differentially expressed genes (DEGs). (B) Functional enrichment analysis of 460 downregulated genes, including Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG), revealed their involvement in EMT-related pathways

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