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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Streptococcus pneumoniae disrupts the structure of the golgi apparatus and subsequent epithelial cytokine response in an H2O2-dependent manner

Fig. 2

Deletion of the pneumococcal peroxidase rescues Golgi integrity. BEAS-2B cells were infected with Spn D39 WT or Spn D39 ΔspxB or left untreated. Cells were fixed and fluorescence stained for Golgin-97 and the nucleus (DAPI). A Immunofluorescence images of infected and uninfected cells. B Quantification of the Golgi surface area, relative to uninfected controls. C 16 h post infection, mitochondrial activity was assessed by MTT assay. (Statistics: paired two-tailed t-test for ΔspxB vs. WT; * = p < 0.05; Scale: 10 µm; at least 500 cells from 4 independent experiments were quantified)

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Cell Communication and Signaling

ISSN: 1478-811X