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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Bone mesenchymal stem cell extracellular vesicles delivered miR let-7-5p alleviate endothelial glycocalyx degradation and leakage via targeting ABL2

Fig. 2

bMSCs alleviate LPS-induced endothelial glycocalyx (EG) degradation and leakage in vitro. A Immunofluorescence images of syndecan-1(red) expression in human umbilical vein endothelial cells (HUVECs); blue: DAPI. Scale bar: 50 μm. B Western blot images and quantitative analysis of the syndecan-1 levels in HUVECs compared with that of Actin (n = 3). C qRT-PCR analysis for fold changes of syndecan-1 gene expression to that of gapdh in HUVECs (n = 3). D Transendothelial resistance value to baseline (0 h) in HUVECs, X-axis: time (h) (n = 3). All results were obtained at 6 h after LPS administration. Values are presented as mean ± sems. Statistical analysis: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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Cell Communication and Signaling

ISSN: 1478-811X