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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: The deubiquitinase EIF3H promotes hepatocellular carcinoma progression by stabilizing OGT and inhibiting ferroptosis

Fig. 6

Increased OGT expression reverses the effect of EIF3H depletion. A Cell proliferation assay of LM3. B Colony formation of LM3. C Representative images of EdU assay of LM3. D Transwell invasion assay of LM3. E Cell Viability analysis showing the response of EIF3H-knockdown LM3 cells to different concentrations of Erastin with or without OGT overexpression. F Representative images presenting EIF3H- silenced LM3 cells response to Erastin (20 μM) with or without OGT overexpression. G-I Levels of lipid ROS (G), GSH (H), and ferrous iron (I) in EIF3H-depleted LM3 cells with or without OGT overexpression. ***P value < 0.001

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Cell Communication and Signaling

ISSN: 1478-811X