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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Characterization of the skin keloid microenvironment

Fig. 1

Schematic representation of the keloid microenvironment. The keloid microenvironment includes keratinocytes, fibroblasts, vascular endothelial cells, immune cells, and stem cells with irregularly oriented collagen fibers. Cellular communication in the keloid microenvironment induces the phenotypic and functional reprogramming of KFs, immune cells, and VECs, promoting collagen production via increased TGF-β production

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